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    Home » Recipes » Italian Pork Recipes

    Italian Cast Iron Pork Tenderloin

    Published: Jun 10, 2025 by Vinny · This post may contain affiliate links · 1 Comment

    Jump to Recipe Print Recipe

    An easy Italian Cast Iron Pork Tenderloin that can be made for your family in under 30 minutes. It's tender and moist and covered in a simple garlic butter wine sauce!

    Sliced pork tenderloin served on a plate with roasted potatoes and broccoli.

    Check out some more delicious pork recipes like Classic Pork Chop Milanese or Grilled Stuffed Pork Chops!

    Jump to:
    • Why This Recipe
    • Ingredient Notes and Substitutions
    • How to Make Cast Iron Pork Tenderloin
    • Pro-Tips
    • Recipe FAQs
    • What to Serve with Cast Iron Pork Tenderloin
    • More Cast Iron Recipes
    • 📖 Recipe
    • Reviews

    Why This Recipe

    You should make this recipe because of it's easy, it's one-pan, and you can pair it with any vegetable or starch under the sun. With a simple sear in the cast-iron pan, this pork tenderloin can be transferred right into the oven. Then, while cooling, you can use the same pan to make your sauce!

    Everyone needs to have some simple proteins in their lineup for weeknights and this is one of them. You could also consider Italian Chicken Cutlets, Pasta with Sausage and Broccoli Rabe, or Chicken Breast in Lemon Butter Sauce for some simple weeknight meals!

    Ingredient Notes and Substitutions

    Ingredients for the recipe.
    • Pork Tenderloin. This works best with a 1.5 to 2-lb pork tenderloin. If you go with a smaller pork, you'll need to decrease the time in the oven.
    • White Wine. I typically use a sauvignon blanc. You can substitute pinot grigio or chardonnay.
    • Italian Seasoning. You can substitute my homemade Italian sausage seasoning, or use your favorite Italian seasoning.

    *Please see the recipe card below for more information on the ingredients.

    How to Make Cast Iron Pork Tenderloin

    Seasoned pork tenderloin on a cutting board.

    Step 1: Preheat the oven to 375℉. Remove the pork tenderloin from the fridge 30 minutes in advance. Season with Italian seasoning, salt, and pepper.

    Searing pork tenderloin on the cast iron pan.

    Step 2: Heat the cast iron pan to medium high heat. Add olive oil to the pan. Sear the pork tenderloin on each side for 60-90 seconds.

    Pork tenderloin flipped on cast iron pan searing other side.

    Step 3: Place the cast iron in the oven and bake for 15-20 minutes or until the tenderloin reaches 140℉.

    Cooked pork tenderloin resting on a cutting board.

    Step 4: Remove the tenderloin from the pan and rest on a cutting board for 10 minutes. Then slice into ¾ inch slices.

    Sauteing butter and garlic in the cast iron pan.

    Step 5: Place the cast iron pan on the stovetop and bring to medium-low heat. Add the butter and garlic to the pan. Once the butter finishes foaming, add the white wine.

    Simmering white wine butter sauce.

    Step 6: Bring to a simmer and reduce by half. Pour the sauce over the sliced pork tenderloin and serve.

    This Italian Cast Iron Pork Tenderloin pairs perfectly with Italian Lacinato Kale Recipe (Tuscan) and Zucchini Risotto or Creamy Garlic Mushroom Pasta!

    Sliced pork tenderloin served on a plate with roasted potatoes and broccoli.

    Pro-Tips

    1. Take the pork tenderloin out of the refrigerator for 15-30 minutes to bring it closer to room temperature. This will help keep the pork tender and moist and avoid drying it out in the oven.
    2. Dry the pork with a paper towel before seasoning.
    3. I typically sear the pork on "3" sides even though it's a circle. On the 3rd side, I sear for about 30 seconds and then place in the oven.

    Recipe FAQs

    Should I sear Pork Tenderloin?

    Yes. Searing a pork tenderloin is the best way to get a delicious crust while also keeping the center of the tenderloin moist.

    Best cooking method for cooking pork tenderloin?

    The best method is to sear and roast. Let the tenderloin rest after roasting for at least half the time it was cooked.

    What temperature to cook pork tenderloin?

    Roast between 375 to 400 degrees F after searing.

    What to Serve with Cast Iron Pork Tenderloin

    • Vegetables. I love to serve this with roasted broccoli, Sauteed Rapini with Garlic, Garlic Parmesan Green Beans, or a Chopped Brussels Sprout Salad with Pancetta
    • Starch. I always add a starch like Crispy Garlic Parmesan Potatoes or Lemon Spinach Orzo.
    • Salad. This definitely goes well with a Kale and Cannellini Bean Salad or Traditional Caesar Dressing with romaine!

    More Cast Iron Recipes

    • Boneless pork chops cooked on a plate with rosemary and thyme
      PERFECT Cast Iron Boneless Pork Chops
    • chicken breast cooked in cast iron skillet and sliced
      PERFECT Cast Iron Chicken Breast
    • cast iron shrimp with orzo
      Cast Iron Shrimp and Creamy Cilantro Lime Orzo
    • Charred chicken thighs over a bed of creamy orzo.
      Cast Iron Lemon Chicken Orzo Recipe

    Please leave a comment and star rating below in the recipe card! I love to hear what you think of our recipes. Feel free to tag us on Instagram @vindelgiudice.

    📖 Recipe

    Sliced pork tenderloin served on a plate with roasted potatoes and broccoli.

    Cast Iron Pork Tenderloin

    Vincent DelGiudice
    A delicious seared pork tenderloin in a cast iron pan finished with a garlic butter wine sauce. It's perfectly tender and finished in the oven.
    5 from 1 vote
    Print Recipe Pin Recipe
    Prep Time 5 minutes mins
    Cook Time 25 minutes mins
    Total Time 30 minutes mins
    Course Dinner, Main Course
    Cuisine American, Italian
    Servings 4 servings
    Calories 119 kcal

    Equipment

    • 1 large cast iron pan

    Ingredients
      

    • 1 1.5-2lb pork tenderloin
    • 2 tablespoon italian seasoning
    • 1 teaspoon salt
    • ½ teaspoon black pepper
    • 1 tablespoon olive oil
    • 3 tablespoon unsalted butter
    • ⅓ cup white wine
    • 2 cloves garlic, crushed

    Instructions
     

    • Preheat the oven to 375℉. Remove the pork tenderloin from the fridge 30 minutes in advance. Season with Italian seasoning, salt, and pepper.
    • Heat the cast iron pan to medium high heat. Add olive oil to the pan. Sear the pork tenderloin on each side for 60-90 seconds.
    • Place the cast iron in the oven and bake for 15-20 minutes or until the tenderloin reaches 140℉.
    • Remove the tenderloin from the pan and rest on a cutting board for 10 minutes. Then slice into ¾ inch slices.
    • Place the cast iron pan on the stovetop and bring to medium-low heat. Add the butter and garlic to the pan. Once the butter finishes foaming, add the white wine. Bring to a simmer and reduce by half. Pour the sauce over the sliced pork tenderloin and serve.

    Notes

      1. Take the pork tenderloin out of the refrigerator for 15-30 minutes to bring it closer to room temperature. This will help keep the pork tender and moist and avoid drying it out in the oven.
      2. Dry the pork with a paper towel before seasoning.
      3. I typically sear the pork on "3" sides even though it's a circle. On the 3rd side, I sear for about 30 seconds and then place in the oven.

    Nutrition

    Calories: 119kcalCarbohydrates: 2gProtein: 0.5gFat: 12gSaturated Fat: 6gPolyunsaturated Fat: 1gMonounsaturated Fat: 5gTrans Fat: 0.3gCholesterol: 23mgSodium: 876mgPotassium: 49mgFiber: 1gSugar: 0.1gVitamin A: 305IUVitamin C: 1mgCalcium: 47mgIron: 1mg
    Tried this recipe?We'd love for you to Leave a Review!

    More Italian Pork Recipes

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      Sausage and Lentil Soup
    • Stuffed Mushrooms on a plate.
      Italian Sausage Stuffed Mushrooms
    • Pork chop milanese over a greens salad and a wedge of lemon on the side.
      Classic Pork Chop Milanese
    • Rice dressing in an oven dish with a spoon.
      Rice Dressing with Sausage

    Reader Interactions

    Comments

    1. Vinny

      June 13, 2025 at 4:59 pm

      5 stars
      This is one of my favorite meals to make for a weeknight meal for the family. Easy and affordable!

      Reply
    5 from 1 vote

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    Recipe Rating




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    Vinny in the Kitchen.

    Vinny DelGiudice, MS CCC-SLP

    My name is Vinny. I am an Italian-American home cook, a photographer, and previously, a speech pathologist specializing in swallowing and voice disorders. I share the recipes I grew up eating in my home and the recipes that I cook for my family. Always From Scratch is about cooking homemade meals and eating with family.

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